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The drugs well-known appetite suppression sometimes seems to lose its grip around cycle time

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

The mechanism is now partly unsupported: Retractions have undermined some of the primary HGF/c-Met synaptogenesis data [4] , and the surviving oral-activity characterization paper carries a 2021 Notice of Concern [2]

This could include: Heart rate assessment at 4-8 weeks after initiation or dose escalation Periodic electrocardiography if arrhythmias are suspected Patient self-monitoring of pulse if symptomatic palpitations occur Evaluation of heart rate control in patients with atrial fibrillation When evaluating tachycardia in patients on GLP-1 therapy, clinicians should assess for other potential causes, including dehydration (especially from GI side effects), anemia, hyperthyroidism, stimulant use, infection, or other medications