This is consistent with experimental data in mice [17,18] and in the human study [19]
Statistical analysis An intent-to-treat approach was used during the statistical analysis of this study
Furthermore, emerging research has elucidated the significance of interaction between lactyl-CoA synthetase and lactyltransferase within the nucleus, which can facilitate the lactylation of histone H3 at lysine 18 (H3K18), such as ACSS2 and KAT2A, as well as GTPSCS and p300
[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Aaron S.D., Vandemheen K.L., Maltais F., Field S.K., Sin D.D., Bourbeau J., Marciniuk D.D., FitzGerald J.M., Nair P., Mallick R