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Although further studies are still needed to fully understand the different contributions of these molecular actors into the pathophysiology of DS, the hope is that they will lead to a better understanding of the molecular mechanisms underlying the pathology of DS, and thus to the development of more effective therapy that will bring amelioration or prevention of cognitive deficits in people with DS

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10.3390/agriculture12010015 5 ChenY.LuZ.FengJ.ChenZ.LiuZ.WangX.et al (2023)

Other mechanisms In addition to the aforementioned well-established therapies, numerous other pharmacological agents, chemical compounds, proteins, and methodologies that have not yet been implemented in clinical practice are currently being investigated to restore the Th17/Treg balance to treat AR (Table 6)