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Unlike many current treatments that focus primarily on glucose control, HTD-1801 is positioned as a potential cardiovascular-kidney-metabolic (CKM) therapy, aiming to improve glycemic control while also affecting lipid metabolism and inflammation through the gut-liver axis

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Its primary mechanism is believed to pivot around enhancing lipolysis, the breakdown of fat, and suppressing lipogenesis, the process of fat accumulation [More et al., 2014]