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# While weight loss drugs seem like a boon to fertility, all of those currently on the marketnot just GLP-1sare contraindicated for pregnancy

Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis

A 2023 pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) found that semaglutide-associated pancreatitis reports disproportionately occurred in the first 90 days of therapy, with a reporting odds ratio of 2.11 (95% CI 1.7-2.6) compared with non-GLP-1 antidiabetic drugs

[7] Novo completes $16.5bn takeover of Catalent, PharmaPhorum , Dec