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There also may be a mental component at play for some men, said Jamin Brahmbhatt, a urologist at the Orlando Health Medical Group: Maybe some men are just feeling themselves more once their body adjusts to the medication

It achieves this by efficiently transporting fatty acids into the mitochondria, the cells powerhouse, where these fatty acids are oxidized to generate energy

However, the potential reduction in healthcare resource use across both classes suggests a combination of both SGLT2is and oral GLP-1 RAs may confer long-term cost savings compared to SGLT2is and standard of care alone [32, 33]

10.1186/s12933-025-02767-9 11 CollaboratorsG