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Recent advances have shown that Rac1 GTPase is a major master regulator of cell motility through regulating the generation of reactive oxygen species and cortical actin reorganization, which are induced by regulating nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity [34]

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125 A recent meta-analysis summarized the efficacy of CoQ10 in patients with pathologies, in which inflammation is a common factor, like cardio-cerebral vascular disease, multiple sclerosis, obesity, renal failure, rheumatoid arthritis, diabetes, and fatty liver disease