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Other studies found that rats given a GLP-1 agonist drank less alcohol, and their brains were less affected by dopamine when they did drink, suggesting it was no longer as desirable for them

Kathiresan S, Melander O, Guiducci C, Surti A, Burtt NP, Rieder MJ, Cooper GM, Roos C, Voight BF, Havulinna AS, Wahlstrand B, Hedner T, Corella D, Tai ES, Ordovas JM, Berglund G, Vartiainen E, Jousilahti P, Hedblad B, Taskinen MR, Newton-Cheh C, Salomaa V, Peltonen L, Groop L, Altshuler DM, Orho-Melander M

doi: 10.1016/j.ghir.2004.03.006 14 JaffeCATurgeonDKFribergRDWatkinsPBBarkanAL

An open trial that included 32 women with PCOS found a multi-nutrient supplement providing 400 mcg (680 mcg DFE) 5-MTHF daily for three months decreased homocysteine levels compared with no treatment