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2022 Grade B recommendation), (2) the proposed mechanism overlap between what GLP-1 medications appear to suppress and what energy-based devices stimulate, and (3) the Catalfamo 2025 case series (PMID 40806889) showing in-clinic bipolar RF is effective for the skin laxity component of Ozempic face, which suggests the mechanism is RF-responsive even if the at-home device delivers less energy than a clinical equivalent

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Best workout timing on injection day If you inject in the morning, schedule your workout for the afternoon or evening