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Ci aumenta la concentrazione di malonil-CoA, il primo intermedio nella sintesi degli acidi grassi, portando all'inibizione della carnitina aciltransferasi 1, impedendo cos l'ingresso di acidi grassi nella matrice mitocondriale per la ossidazione

Metformin activates glucose and mitochondrial metabolism while GLP-1 agonist tend to lower blood sugar levels through incretin hormones by slowing down gastric emptying

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Its antipsoriatic activity was assessed using imiquimod-induced Wistar rats [155, 156]