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ROS-lowering doses of vitamins C and A accelerate malignant melanoma metastasis

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GSTM1 vs GSTT1: Different Enzymes, Overlapping Roles GSTM1 and GSTT1 are structurally related but belong to different GST subfamilies mu (GSTM) and theta (GSTT) with overlapping but not identical substrate profiles in estrogen metabolism: GSTM1 (Glutathione S-Transferase Mu 1) is highly expressed in liver, lung, and other metabolically active tissues

Because it also wards off free radicals, it may take some of the pressure off of glutathione to do the job, thus freeing it up to perform its miracles elsewhere