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Ca 2 acts as a universal secondary messenger, translating external and internal stimuli into specific cellular responses, with distinct temporal and spatial signatures depending on stress type, hormonal signals, or light conditions (Zhang et al

Lung and Kidney Our findings using non-human primate kidney tissue, as shown in Figure 6, demonstrate that GLP-1Rs are exclusively expressed in smooth muscle cells in the walls of arteries and arterioles, and studies with human tissue show the same (73, 87)

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