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You should seek prompt medical advice if you experience any of the following whilst taking a weight loss supplement: Chest pain, palpitations, or irregular heartbeat Severe headache or sudden rise in blood pressure Allergic reactions such as rash, swelling, or difficulty breathing Significant gastrointestinal symptoms Mood changes, anxiety, or sleep disturbance Jaundice, dark urine, or severe abdominal pain (which may indicate liver injury) Any suspected adverse reactions to supplements should be reported to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk

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doi: 10.1186/s40360-017-0136-7