The use of compounded drugs in patients using GLP-1s without medical supervision pose significant risk and can result in significant consequences, said Marina Basina, MD, a clinical professor in endocrinology, gerontology and metabolism

HOW TO IMPROVE RESULTS & REDUCE SYMPTOMS To maximize effectiveness and minimize common side effects, small lifestyle and recovery adjustments can make a meaningful difference: Prioritize protein intake to support satiety, muscle preservation, and metabolic health Stay well hydrated, especially during dose adjustments, to support digestion and detox pathways Build and preserve lean muscle through resistance training or strength-based movement Increase daily physical activity to enhance insulin sensitivity and fat metabolism Optimize sleep to regulate hunger hormones and support recovery Stack supportive MATTR modalities, such as Lymphatic Drainage to aid detoxification, ARRC Elysium Light Bed to boost immune function, Cryotherapy for inflammation and fat activation, HBOT for cellular recovery, and CVAC to enhance circulation, oxygen utilization and metabolic conditioning These strategies help create a more supportive internal environment, allowing GLP-1 and GIP therapies to work more effectively while promoting sustainable, long-term body recomposition and metabolic health

2016;311(2):H33746
Either T-RDN or A-RDN attenuates increases in MAP and HR responses to GLP-1 MAP and HR were significantly increased during intravenous infusion of GLP-1 in both Sham and HF rats