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A 2013 meta-analysis of 17 randomized, placebo-controlled studies in a total of 1,625 participants with heart failure found that oral L-carnitine (1.5-6 g/day for seven days to three years) significantly improved several measures of cardiac functional capacity (including exercise tolerance and markers of the left ventricle function), yet had no impact on all-cause mortality (56)

Now, the trial just needs to get fully funded

doi:10.3988/jcn.2021.17.1.1

You can read more about sitagliptin on the NHS website Pregnancy, breastfeeding and fertility while taking sitagliptin Medications include: GLP-1 therapy (glucagon-like peptide-1 receptor agonists) Dulaglutide ( as Trulicity ) Exenatide ( as Bydureon ) Liraglutide ( as Diavic or Victoza for Type 2 diabetes and Saxenda for weight loss) Semaglutide ( as Ozempic for type 2 diabetes and as Wegovy for weight loss) Dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 agonist Tirzepatide as Mounjaro Guidance from the MHRA published in June 2025 states GLP-1 medicines should not be taken by people who are breastfeeding