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Darmstadt, Germany) or Honeywell (Seelze, Germany), formic acid and ammonium bicarbonate for LC-MS from Honeywell, dithiothreitol (DTT) from Pierce Biotechnology (Rockford, IL, United States), iodoacetamide from Sigma-Aldrich (St

Carnitine levels in skeletal muscle, where more than 95% of the total carnitine is stored ( 30 ), as well as in the heart, were significantly (p=0.01) lower in SLC25A45 KO than in control mice ( Fig

We would also like to sincerely thank our patients and their guardians for participation in the study

Although acid labile linkers provide ADCs with precise drug release and high selectivity, they still face multiple challenges during development