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Dosing dihexa before complete clearance (within six to eight hours of the previous dose) produces overlapping plasma concentration curves and higher peak concentrations, but does not significantly extend the effective half life because metabolism continues at the same rate

doi: 10.2337/db16-1099 269 BinBHFukadaTHosakaTYamasakiSOhashiWHojyoSet al

High blood potassium levels and symptoms related to polycythemia vera, a blood disorder, can occur

However, more serious consequences, such as iron overload and kidney stones, may also result from taking excessive amounts of vitamin C ( Fortunately, you can easily prevent these potential side effects by avoiding high dose vitamin C supplements