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GORD is a recognised side effect of GLP-1 receptor agonists, occurring because delayed gastric emptying may increase pressure within the stomach and promote reflux of acidic contents into the oesophagus

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Two of the most prominent brain changes are (1) the accumulation of the protein fragment betaamyloid into clumps (called betaamyloid plaques) outside neurons and other brain cells and (2) the accumulation of an abnormal form of the protein tau (called tau tangles) inside neurons

The ability to adjust circadian rhythms could lead to more consistent and rejuvenating sleep experiences