Your healthcare provider can help you weigh the benefits of continuing the medication against the severity of the side effects and may suggest dosage adjustments, lifestyle changes, or additional treatments to mitigate these effects
In the STEP 1 trial extension, participants who stopped semaglutide after 68 weeks regained roughly two-thirds of their prior weight loss within a year, and related cardiometabolic improvements moved back toward baseline
Articles were excluded if they were not written in the English language, did not have a registered digital object identifier (DOI), were a letter to the editor or an abstract-only publication, did not directly assess the use of GLP-1 RAs in psoriasis or HS, were duplicate studies, or were inaccessible through institutional resources
For weight loss, the injections are approved for people with a BMI of 27 and above, and weight loss surgery is approved for a BMI of 30 and above, though its more common among people with with a BMI over 35