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We proposed to make this policy budget neutral under the OPPS through the second wage index budget neutrality adjustment applied to the OPPS conversion factor (which currently includes the 5 percent hold harmless cap policy)

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Disruption of protein homeostasis is recognized as a hallmark of aging [70], and previous studies have shown that impaired ovarian angiogenesis and vascular remodeling contribute to inadequate follicular development and ovarian aging [71]

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