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PLoS One 14, e0214727

Fura-2 emission was obtained by exciting alternatively at 340 and 380 nm with a rotating filter wheel (Sutter Instruments) and by monitoring emissions (F340 and F380) at 510 nm

The current recommendation: do not prescribe Wegovy to a child under 12 outside of a clinical trial or a carefully documented, individually justified off-label protocol with enhanced safety monitoring, and check ClinicalTrials.gov (identifier search: semaglutide AND pediatric) for new enrollment opportunities before initiating off-label therapy