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10.2337/dc19-1745 28 GersteinH
The story lies in the magnitudes of both changes
Many people notice reduced hunger early on, with visible weight loss typically starting around 4 to 8 weeks into treatment and continuing as the dose is increased toward the 25 mg maintenance level
(Folate deficiency disrupts normal DNA synthesis and methylation, which interferes with cell division and development, especially in rapidly dividing embryos.) Megaloblastic anemia, which can lead to symptoms like fatigue, weakness, and difficulty concentrating Elevated homocysteine, even when B12 levels are normal
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