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Taken together, this evidence suggests that the heterogeneity of studies models and the interaction of many adaptive mechanisms might explain the variable results in the recent studies concerning the influence of SGLT2-i treatment on the RAAS, although an activation of intrarenal RAS in chronic treated patients has been excluded (42)

These GLP-1 receptor agonists offer impressive health benefits, from better blood sugar control to significant weight reduction

Recent studies have shown that GLP-1 use is associated with a reduction in cases of dementia among people with type 2 diabetes (something that's likely to also be true in a broader population of people at risk for dementia)

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