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It is a coherent and attractive model, but it is assembled from in-vitro and animal fragments

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Based on mouse strain differential susceptibility to phenobarbital promotion of DEN-initiated hepatocarcinogenesis, the authors compared the effects of phenobarbital in drinking water on hepatic microsomal protein concentrations in four strains of mice

The unsupervised clustering of 4453 fibroblasts was used to analyze the senescent cells in keloid and normal skin fibroblast based on senescence-associated marker genes, CDKN2A, TP53, CDKN1A (also known as p21 ) , LMNB1, H2AFX, TP53BP1, SFRP4, CCND1 and GLB1 according as previously reference 20,21