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Figure 2: Around half of GLP-1 side effects are gastrointestinal GLP-1s have previously been suggested to be linked to self-harm and suicidal thoughts, but the MHRA concluded in September 2024 that the available data do not support a causal association between GLP-1s and depression, suicidal ideation and suicide, following a review by the European Medicines Agencys pharmacovigilance risk assessment committee 24

H., van Bockxmeer, F

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Because colistin is a substrate of the carnitine/organic cation transporter 2 (OCTN2, SLC22A5 ), we also considered the possibility that co-incubation with L-carnitine reduced colistin intracellular accumulation and toxicity