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Prior to the trial, the older cohort exhibited severe intracellular glutathione deficiency, massive oxidative stress, and impaired mitochondrial function compared to young, healthy controls

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A lower GSH:GSSG ratio may indicate increased oxidative burden, environmental stress exposure, metabolic strain, or impaired recovery capacity

For context, Cigna employs roughly 60,000 people in the US, though its unclear how many were covered for weight loss drugs under the companys employee health plan