Research indicates that semaglutide may offer better protection for the heart and kidneys compared to some other GLP-1R agonists
Moreover, relevant data from product monographs were also reviewed
One notable barrier is that GLP-1 receptor agonists have historically been administered via SC injection only
Long-term side effects linked to Saxenda: Gastroparesis (stomach paralysis) Ileus (intestinal blockages) Gallbladder problems, including gallstones (symptoms include severe abdominal pain, diarrhea, pale-colored stool, fever, nausea, vomiting, jaundice) Increased heart rate (heart palpitations, chest pain) Pancreatitis (sudden upper abdominal pain, persistent severe burning pain in the abdomen, vomiting) Suicidal thoughts or behavior (new or worsening depression, thoughts about harming yourself or ending your life, changes in mood or behavior) Kidney failure Low blood sugar Risk of thyroid cancer Severe allergic reaction Saxenda and Vision Loss A recent study in JAMAs Ophthalmology found semaglutide drugs could cause a specific sort of eye condition called NAION