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In a randomized clinical trial, tesamorelin reduced visceral adipose tissue and liver fat in HIV-infected patients (Stanley et al., JAMA, 2014), and its Phase 3 program (Falutz et al.) established the visceral-fat effect that underpins its FDA approval

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Nitric oxide plays critical roles in vascular tone regulation, mucosal protection, immune modulation, and neural signaling which helps explain why BPC-157s effects appear across such diverse tissue types