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Mol Metab 54:101352 Tan HL et al (2024) Leptin-activated hypothalamic BNC2 neurons acutely suppress food intake

Pancreatitis: In rare cases, semaglutide may cause acute inflammation of the pancreas, known as pancreatitis

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NOEL = 3 mg/kg body weight per day 1.3 Conclusions and recommendations Considering the toxicological characteristics of chlorothalonil, both qualitatively and quantitatively, it was concluded, on the basis of the NOEL of 3 mg/kg body weight per day derived in the 2-year study on dogs and applying a 100-fold uncertainty factor, that 0.03 mg/kg body weight per day will probably not cause adverse effects in humans by any route of exposure