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Disrupted cortisol patterns help explain many of the symptoms long COVID patients consistently report, including: Fatigue Sleep dysfunction Inflammatory amplification Poor stress resilience Gut Microbiome Disruption COVID-19 causes significant gut microbiome disruption during acute infection, and research shows this disruption can persist for months in long COVID patients

Rania F, Abdelhamid O, Elsenosi Y, Abdelmagid AD, Said A (2024) Biochemical and histopathological evaluation of the potential ameliorating effects of Spirulina platensis against acute hepatorenal toxicity of diclofenac sodium in male rats

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