Jump to: Side effects by dose | Stomach and gut side effects | Heart rate and irregular heartbeats | Dysesthesia: skin sensation changes | Muscle loss during rapid weight loss | Mental health and mood | Drug interactions and contraception | Other side effects | How retatrutide compares to Mounjaro and Wegovy | Discontinuation and weight regain | What we dont yet know | When to speak to a healthcare professional | FAQ | Take home message | Second Natures Mounjaro programme | References Retatrutides side effects fall into three main groups: stomach and gut symptoms during dose increases, a heart-rate increase larger than other GLP-1 medications, and a skin sensation called dysesthesia that emerged at higher doses in Phase 3 trials

A 41-year-old woman with brain fog, insomnia, vertigo, neuropathic symptoms, blood pressure lability, postural orthostatic tachycardia syndrome (POTS), dermatographism, macular erythematous rash, flushing, burning skin, severe gastroesophageal reflux, migratory joint pains, vaginal pruritus, intermittent hoarseness, and chemical sensitivity
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The therapeutic potential of curcumin: a review of clinical trials