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More specifically, we will discuss the current methods of neurotherapeutic brain stimulation such as DBS, experimental and clinically relevant methods such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and theta burst stimulation (TBS), and emerging methods of stimulation such as optogenetics, near-infrared, and magnetothermal DBS

Plant extracts like berberine show modest, short-lived indirect effects and the NIH notes that berberines role in GLP-1 production has not been clinically validated at supplement doses

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