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In the liraglutide group, 71.9% of the patients lost more than 5% of their body weight, but only 8.8% of patients in the placebo group lost more than 5% of their weight [49]

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While direct hepatic effects have been proposed, human hepatocyte GLP-1 receptor expression is limited, and most hepatic benefits correlate with weight loss and improved metabolic parameters rather than direct receptor-mediated effects