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An insufficiency of iodolactone may help explain why both iodine deficiency and iodine excess are, paradoxically, associated with triggering or exacerbating autoimmune thyroiditis, given the role iodolactone has in protecting the thyroid from oxidative damage and in cell-cycle regulation

of this final rule with comment period where we finalize with modification our cross-program proposal to codify updates to the Extraordinary Circumstances Exceptions (ECE) policy for the REHQR Program