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Moreover, this effect is most pronounced in the oldest flies (30 days old at time of APAP administration) and is observed in both males and females (Fig

On the other hand, the gdh3 / gdh3 mutant showed similar growth kinetics to the wild-type cells when grown on arginine as the sole carbon and nitrogen source, but the gdh2 / gdh2 strain showed minimal growth (0.009 h 1 ) and biomass yield (0.016 g L 1 ) compared to the wild-type strain (growth rate = 0.068 h 1 , biomass = 0.50 g L 1 )

With small reductions in weight of even of 1% weight loss noted in the literature to have reductions in progression

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