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Study termination Primary efficacy endpoint achieved: Completion of 1 year of tirzepatide treatment Complete pathological remission (defined as no evidence of hyperplasia or malignancy on follow-up endometrial biopsy), allowing the patient to proceed with pregnancy planning

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This study evaluated the therapeutic potential of non-gene-edited human chemically induced pluripotent stem cell-derived neural stem cells (hCiPSC-NSCs) in a prenatal valproic acid (VPA)-induced rat model of ASD, using a dual-pathway administration strategy (intravenous systemic delivery combined with an intracerebroventricular boost)