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Nutrients , 14 (15), 3214
2.4 Statistical analysis Statistical analyses were conducted in RStudio (version 4.2.1
Circadian pathway Modulation of the circadian rhythm Regulates sleep-wake cycles Normalizes sleep disorders Effects lasting several days Opioid route Endogenous opioid system Pain perception module Blocked by naloxone Supports weaning management Stress response Hypothalamic-pituitary-adrenal axis Reduces stress responses Reduces cortisol secretion Improves stress management Unique biological properties Unlike most peptides, DSIP freely crosses the blood-brain barrier and can be absorbed by the intestine without enzymatic degradation
Sun W, Jia M, Feng Y, Cheng X
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