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A 2024 Swedish study followed 3,249 MS patients for an average of 10.6 years and found that obesity was associated with: 3 43% higher risk of reaching EDSS 3 (moderate disability) 40% higher risk of reaching EDSS 4 (significant walking impairment) More rapid cognitive decline Higher MRI activity showing new brain lesions A German study of 1,066 MS patients found even more striking results: obese patients reached disability milestones nearly 50% faster than those with normal weight

The medication, however, has serious side effects

Although MVMR was conducted to account for potential confounding by BMI and T2DM, several methodological limitations precluded its reliable interpretation

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