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Notably, COF-909-Cu also displays GPx-like activity by depleting intracellular GSH, thereby suppressing H 2 O 2 scavenging and significantly elevating intracellular H 2 O 2 levels

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However, theyre not considered sensitive, nor specific, and tend to only identify IDA not the early stages of iron depletion ( Identifying the earlier stages of depletion is beneficial, as doing so allows you to address the problem immediately be it through diet modifications or supplements rather than letting it progress to IDA before taking action