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Name: glp 1 drug makers Patients' Use GLP-1 Drugs for Weight Loss, Benefit Gains What GLP-1 Drugs Teach Us
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doi: 10.1161/01.CIR.101.24.2829

1 Physiological changes during pregnancy may unmask asymptomatic CVD such as chronic hypertension or prediabetes

Preclinical data suggest that the timing of GLP-1 receptor agonist administration may influence metabolic alignment: in mice subjected to circadian misalignment through light-phase feeding, exenatide administered at the onset of the active period (ZT 12) counteracted the phase-shifting effect on the hepatic clock, whereas dosing at the rest-phase onset (ZT 0) exacerbated circadian disruption [71]