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Biomarkers like albumin, prealbumin, and nitrogen balance, combined with genetic predispositions in appetite and metabolic signaling, inform safe protein dosing

2 REDEFINE 2 was a double-blind, randomized, placebo-controlled 68-week phase 3 trial that evaluated the efficacy and safety of once-weekly CagriSema versus placebo, both along with lifestyle intervention in 1,206 adults with type 2 diabetes and either obesity or overweight

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Hyperglycemia or Hypoglycemia with Changes in Insulin Regimen: Changes in an insulin regimen (e.g., insulin strength, manufacturer, type, injection site or method of administration) may affect glycemic control and predispose to hypoglycemia or hyperglycemia