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Methods A total of 147 women with PCOS were randomly assigned into two groups: the combo group ( n = 72) received a combination of metformin, pioglitazone, and ALC (500 mg, 15 mg, and 1500 mg, respectively), twice daily

Rare side effects include pancreatitis, acute kidney injury, worsening diabetes-related retinopathy and medullary thyroid cancer

People taking GLP-1 medications may experience a range of positive effects: Lower blood sugar levels, leading to improved diabetes control Promote weight loss, which can improve overall health and lower the risk of related medical problems Lower the risk of heart attacks, strokes, and kidney disease in people with diabetes or those at high cardiovascular risk Improve liver health in people with metabolic dysfunction-associated steatotic liver disease (MASLD) Help lower blood pressure and cholesterol, supporting overall heart health Reduce appetite and food cravings, making healthy eating patterns easier to maintain Less likely than some other diabetes medicines to cause low blood sugar or unwanted weight gain Can provide meaningful and lasting results for people who have struggled to lose weight with lifestyle changes alone Are there specific lifestyle changes that work best with these medications

Castel Santana, regional medical director at 10X Health, a health and wellness company that offers peptides, said he feels confident that most peptides have "minimal or low" associated risk based on his personal experiences prescribing them