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Clinical translation would require trials in cardiac patient populations with appropriate safety monitoring given theoretical concerns about blood pressure effects and vascular remodeling

Tamer Coskun is the principal scientist who led the discovery, preclinical development, and early clinical proof-of-concept studies for GLP3

Concurrently, Drp1-mediated mitochondrial fragmentation significantly reduces synaptic ATP production, directly impairing synaptic transmission efficacy

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