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In lupus-prone females, reduced abundance of Erysipelotrichaceae and Bifidobacterium, with increased Lachnospiraceae and Bacteroidetes S247 abundance, has also been reported ( These findings suggest that microbiological dysbioses specific to sex, more precisely the increased prevalence of Lachnospiraceae in females, may account for the earlier onset and greater severity of lupus symptoms

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Exhibit 10 As of February 2017, 39 FIDE SNPs were operating in eight states (Arizona, California, Idaho, Massachusetts, Minnesota, New Jersey, New York, and Wisconsin), with a total enrollment of 136,677 dual eligible beneficiaries (CMS, 2017a)