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For both HC and patients, purine metabolites normally show significant cross-pathway correlation only with TYR, not with its metabolites, where correlations may be lost due to internal influences over neurotransmitter production
The brain possesses the capability to exert influence on the structural and functional organization of the gut microbiota
The structural model contains 12 polypeptide chains in the asymmetric unit, corresponding to three tetramers of MSA-DH
Some studies also point to its role in supporting brain-derived neurotrophic factor, a protein that helps neurons survive and form new connections
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