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A B12 shot is not a stimulant, so you should not expect a sudden caffeine-like jolt minutes after your appointment

Some side effects that are more serious than others are: Chills Fever Fatigue Tachycardia (Heart rate that is too fast) Diarrhea Fever with lowered white blood cell count Swelling in the body (most often in the legs and feet) Low blood pressure (hypotension) with a skin rash Alopecia (hair loss that is temporary or permanent) Infection Low levels of oxygen in the body (hypoxia) Shortness of breath After finishing lifileucel treatment, it is important to stay within two hours travel time of the treatment location

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Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the wisconsin oncology network