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It has a 94% structural similarity to glucagon-like peptide (GLP)-1 and binds the GLP-1 receptor with an affinity of 0.38 nM
GLP-1 medications carry a boxed warning that has made many patients uneasy, but the warning is often misunderstood
For patients who were overweight or obese, the incidence was 6.7% with semaglutide compared to 0.8% with non-GLP-1 weight-loss medications
Some consumers claim that Novo Nordisk should have been more thorough, proactive, and transparent about investigating and disclosing these and other warnings about its product
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