If you've had your gallbladder removed, using semaglutide or other GLP-1 medications requires careful consideration of how your digestive system has changed
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Phase 2 NEJM titration (still common in research) Phase 2 retatrutide titration schedule Phase Initiation Weeks Weeks 1-4 Weekly Dose 1 mg Phase Early escalation Weeks Weeks 5-8 Weekly Dose 2 mg Phase Mid escalation Weeks Weeks 9-12 Weekly Dose 4 mg Phase High escalation Weeks Weeks 13-16 Weekly Dose 8 mg Phase Maximum Weeks Weeks 17+ Weekly Dose 12 mg Source: Jastreboff et al., NEJM 2023
sativa key compound, acts as a partial agonist to the cannabinoid receptors CB1 and CB2 (Mecha et al., 2020), displaying anti-inflammatory and neuroprotective properties, suppressing the IFN, IL-17, IL-6, IL-1, and TNF- production in the brain and preventing the infiltration of immune cells into the CNS