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Accidental injection of high dose (1:1,000) epinephrine contained in epinephrine autoinjectors into fingers or thumb can produce prolonged tissue ischemia, reperfusion pain, and in some cases traumatic nerve injury (neuropraxia) lasting as long as 8-10 weeks (Fitzcharles-Bowe et al, 2007

RAMP2 influences glucagon receptor pharmacology via trafficking and signaling