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Description

Recent studies have revealed that cancer cells can transfer damaged mitochondria to TILs, profoundly impairing their antitumor functions ( 4.2.2 Dendritic cells Increasing cholesterol levels, either through a cholesterol-rich diet, apolipoprotein E (APOE) ablation, or inhibition of cholesterol efflux by LXR suppression, impairs dendritic cell migration ( Cholesterol inhibits stimulator of interferon genes (STING)-dependent antitumor activity by disrupting STING signaling in monocyte-derived dendritic cells

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Deficitul de carnitin Deficitul de carnitin este rar i cel mai adesea rezult din probleme genetice asociate cu anomalii n mecanismul de transport al carnitinei sau din cauza unei boli (de exemplu, insuficien renal cronic)

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